The synthesis of dextroamphetamine involves solid multi-step process starting from D-phenylalanine https://eurekathinklabs.com/dextroamphetamine-decoding-the-chemistry-and-medicinal-significance/
Starting Material: The synthesis begins with D-phenylalanine, whom serves as the precursor for the production of dextroamphetamine sulfate besides methamphetamine hydrochloride.
Reaction Sequence: The reaction sequence proceeds through three intermediates, involving the alteration of the eternal configuration of the asymmetric carbon atom while maintaining the comparative configuration. This process leads in order the formation of dextroamphetamine sulfate and methamphetamine hydrochloride.
Intermediate Alteration: The synthesis involves altering the reductive conditions employed for the dismissal of solid carbamate retaining group to obtain or dextroamphetamine sulfate or methamphetamine hydrochloride from the decision common intermediate.
Specific Chemical Reactions: The characteristic chemical reactions involved in the synthesis concerns the conversion of benzene into allylbenzene, substitution of all CN group in order form the cyano compound, reduction to an amine, besides elongation of the chain taking advantage alkynyl anion in order to form an alkene.
Patent Information: There predisposed patent-related information available regarding the process for the synthesis of amphetamine derivatives, connecting dexamphetamine, prymenav specific reaction conditions besides coupling agents.
Literature References: The synthesis process owns been documented in scientific literature, including the Journal of Pharmaceutical Sciences, with thorough information about the synthesis of dextroamphetamine sulfate besides methamphetamine hydrochloride from D-phenylalanine.